Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
NF2 P35240 neurofibromin 2 1.00 0.468 0.885
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
ACACA Q13085 acetyl-CoA carboxylase alpha 1.00 0.480 0.846
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
VCAN P13611 versican Extracellular structure 1.00 0.497 0.808
ROCK2 O75116 Rho associated coiled-coil containing protein kinase 2 Kinase 1.00 0.529 0.808
F8 P00451 coagulation factor VIII Enzyme 1.00 0.542 0.769
EIF4G1 Q04637 eukaryotic translation initiation factor 4 gamma 1 Nucleic acid binding 1.00 0.553 0.808
REV3L O60673 REV3 like, DNA directed polymerase zeta catalytic subunit 1.00 0.588 0.654
ASXL2 Q76L83 ASXL transcriptional regulator 2 1.00 0.617 0.692
PPP1R12A O14974 protein phosphatase 1 regulatory subunit 12A 1.00 0.626 0.615