Disease: Bicuspid aortic valve
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE2 Q9BYF1 angiotensin I converting enzyme 2 Enzyme 1.00 0.477 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
B3GAT3 O94766 beta-1,3-glucuronyltransferase 3 Enzyme 2.7E-08 0.621 0.538
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
CHST3 Q7LGC8 carbohydrate sulfotransferase 3 7.2E-03 0.517 0.846
CLIP2 Q9UDT6 CAP-Gly domain containing linker protein 2 Cellular structure 1.00 0.529 0.808
ELN P15502 elastin 2.1E-14 0.415 0.885
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FBN2 P35556 fibrillin 2 Calcium-binding protein 1.00 0.505 0.808
FLNA P21333 filamin A 1.00 0.419 0.846
FLNC Q14315 filamin C 1.00 0.568 0.615
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808
GTF2IRD1 Q9UHL9 GTF2I repeat domain containing 1 0.90 0.522 0.769
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731
LTBP3 Q9NS15 latent transforming growth factor beta binding protein 3 Calcium-binding protein 0.69 0.564 0.846
MAP3K7 O43318 mitogen-activated protein kinase kinase kinase 7 Kinase 1.00 0.477 0.808
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
PACS1 Q6VY07 phosphofurin acidic cluster sorting protein 1 1.00 0.603 0.615
PLOD1 Q02809 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Enzyme 1.5E-15 0.579 0.731
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923