Disease: Astigmatism
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KCNV2 Q8TDN2 potassium voltage-gated channel modifier subfamily V member 2 Ion channel 1.2E-26 0.736 0.115
GLRB P48167 glycine receptor beta Ion channel 1.4E-03 0.705 0.308
GPR143 P51810 G protein-coupled receptor 143 G-protein coupled receptor 0.93 0.659 0.385
TUB P50607 TUB bipartite transcription factor 3.1E-03 0.659 0.385
NPLOC4 Q8TAT6 NPL4 homolog, ubiquitin recognition factor 1.00 0.743 0.385
BLOC1S3 Q6QNY0 biogenesis of lysosomal organelles complex 1 subunit 3 4.1E-03 0.729 0.385
PACS2 Q86VP3 phosphofurin acidic cluster sorting protein 2 1.00 0.700 0.423
CLDN19 Q8N6F1 claudin 19 Cell-cell junction 5.0E-03 0.659 0.423
ARCN1 P48444 archain 1 Transporter 1.00 0.705 0.462
EMC1 Q8N766 ER membrane protein complex subunit 1 6.7E-26 0.700 0.462
LOXL3 P58215 lysyl oxidase like 3 2.7E-13 0.666 0.462
CACNA1F O60840 calcium voltage-gated channel subunit alpha1 F Ion channel 1.2E-05 0.595 0.500
CHMP1A Q9HD42 charged multivesicular body protein 1A 2.9E-04 0.695 0.500
VARS1 P26640 valyl-tRNA synthetase 1 1.8E-08 0.711 0.500
P4HTM Q9NXG6 prolyl 4-hydroxylase, transmembrane 3.9E-09 0.666 0.500
CLDN16 Q9Y5I7 claudin 16 Cell-cell junction 2.5E-02 0.647 0.538
CREBZF Q9NS37 CREB/ATF bZIP transcription factor 0.10 0.650 0.538
CCDC28B Q9BUN5 coiled-coil domain containing 28B Receptor 3.2E-09 0.659 0.538
TMTC3 Q6ZXV5 transmembrane O-mannosyltransferase targeting cadherins 3 4.6E-05 0.636 0.538
POGZ Q7Z3K3 pogo transposable element derived with ZNF domain Transcription factor 1.00 0.599 0.577
WAC Q9BTA9 WW domain containing adaptor with coiled-coil 1.00 0.686 0.615
SMARCAL1 Q9NZC9 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 2.3E-06 0.599 0.654
MPLKIP Q8TAP9 M-phase specific PLK1 interacting protein 1.6E-04 0.604 0.654
BBS1 Q8NFJ9 Bardet-Biedl syndrome 1 3.4E-12 0.593 0.692
GTF2E2 P29084 general transcription factor IIE subunit 2 Transcription factor 3.9E-02 0.617 0.692