Disease: Ventricular Septal Defects
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808
RNF113A O15541 ring finger protein 113A Enzyme 0.89 0.597 0.769
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846
RAD21 O60216 RAD21 cohesin complex component 1.00 0.528 0.846
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
CDC45 O75419 cell division cycle 45 Nucleic acid binding 4.6E-05 0.588 0.692
SIX6 O95475 SIX homeobox 6 Transcription factor 0.52 0.588 0.654
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
CHRM3 P20309 cholinergic receptor muscarinic 3 G-protein coupled receptor 0.99 0.464 0.885
GTF2E2 P29084 general transcription factor IIE subunit 2 Transcription factor 3.9E-02 0.617 0.692
LRPAP1 P30533 LDL receptor related protein associated protein 1 4.5E-07 0.579 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846