Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BLM | P54132 | BLM RecQ like helicase | 1.5E-15 | 0.535 | 0.808 | |
BMPR1A | P36894 | bone morphogenetic protein receptor type 1A | Kinase | 0.90 | 0.522 | 0.731 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
BRIP1 | Q9BX63 | BRCA1 interacting protein C-terminal helicase 1 | Enzyme | 6.2E-17 | 0.507 | 0.731 |
CDC73 | Q6P1J9 | cell division cycle 73 | 1.00 | 0.543 | 0.615 | |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
CDK4 | P11802 | cyclin dependent kinase 4 | Kinase | 6.3E-02 | 0.412 | 0.808 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CDKN2B-AS1 | CDKN2B antisense RNA 1 | 0.491 | 0.769 | |||
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CTNNA1 | P35221 | catenin alpha 1 | Cellular structure | 0.97 | 0.584 | 0.538 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
DICER1 | Q9UPY3 | dicer 1, ribonuclease III | Enzyme | 1.00 | 0.446 | 0.846 |
FANCC | Q00597 | FA complementation group C | 2.8E-13 | 0.507 | 0.808 | |
FLCN | Q8NFG4 | folliculin | 0.79 | 0.537 | 0.885 | |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
HOXB13 | Q92826 | homeobox B13 | 3.7E-08 | 0.573 | 0.462 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MAX | P61244 | MYC associated factor X | Transcription factor | 0.83 | 0.553 | 0.769 |
MEN1 | O00255 | menin 1 | 1.00 | 0.444 | 0.808 |