Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
C11orf65 | Q8NCR3 | chromosome 11 open reading frame 65 | 2.0E-14 | 0.670 | 0.462 | |
CDC73 | Q6P1J9 | cell division cycle 73 | 1.00 | 0.543 | 0.615 | |
CDK4 | P11802 | cyclin dependent kinase 4 | Kinase | 6.3E-02 | 0.412 | 0.808 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
FLCN | Q8NFG4 | folliculin | 0.79 | 0.537 | 0.885 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MEN1 | O00255 | menin 1 | 1.00 | 0.444 | 0.808 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
RB1 | P06400 | RB transcriptional corepressor 1 | Nucleic acid binding | 1.00 | 0.444 | 0.885 |
SDHB | P21912 | succinate dehydrogenase complex iron sulfur subunit B | Enzyme | 2.4E-04 | 0.474 | 0.846 |
SDHC | Q99643 | succinate dehydrogenase complex subunit C | 2.0E-04 | 0.517 | 0.846 | |
SDHD | O14521 | succinate dehydrogenase complex subunit D | Transporter | 0.34 | 0.472 | 0.885 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |