Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 |
BARD1 | Q99728 | BRCA1 associated RING domain 1 | 1.4E-24 | 0.597 | 0.538 | |
BLM | P54132 | BLM RecQ like helicase | 1.5E-15 | 0.535 | 0.808 | |
BMPR1A | P36894 | bone morphogenetic protein receptor type 1A | Kinase | 0.90 | 0.522 | 0.731 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
BRIP1 | Q9BX63 | BRCA1 interacting protein C-terminal helicase 1 | Enzyme | 6.2E-17 | 0.507 | 0.731 |
CDC73 | Q6P1J9 | cell division cycle 73 | 1.00 | 0.543 | 0.615 | |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
CDK4 | P11802 | cyclin dependent kinase 4 | Kinase | 6.3E-02 | 0.412 | 0.808 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CDKN2B-AS1 | CDKN2B antisense RNA 1 | 0.491 | 0.769 | |||
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CTNNA1 | P35221 | catenin alpha 1 | Cellular structure | 0.97 | 0.584 | 0.538 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
DICER1 | Q9UPY3 | dicer 1, ribonuclease III | Enzyme | 1.00 | 0.446 | 0.846 |
EXT2 | Q93063 | exostosin glycosyltransferase 2 | Enzyme | 1.3E-09 | 0.576 | 0.654 |
FANCC | Q00597 | FA complementation group C | 2.8E-13 | 0.507 | 0.808 | |
FBXO11 | Q86XK2 | F-box protein 11 | Enzyme | 1.00 | 0.604 | 0.692 |
FH | P07954 | fumarate hydratase | Enzyme | 8.8E-02 | 0.489 | 0.846 |
FLCN | Q8NFG4 | folliculin | 0.79 | 0.537 | 0.885 |