Disease: Paraganglioma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
C11orf65 Q8NCR3 chromosome 11 open reading frame 65 2.0E-14 0.670 0.462
CDC73 Q6P1J9 cell division cycle 73 1.00 0.543 0.615
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAX P61244 MYC associated factor X Transcription factor 0.83 0.553 0.769
MEN1 O00255 menin 1 1.00 0.444 0.808
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
SARDH Q9UL12 sarcosine dehydrogenase Enzyme 5.3E-16 0.523 0.846
SDHA P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 2.6E-10 0.517 0.731
SDHAF2 Q9NX18 succinate dehydrogenase complex assembly factor 2 2.8E-06 0.604 0.692
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
SDHC Q99643 succinate dehydrogenase complex subunit C 2.0E-04 0.517 0.846
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
SDS P20132 serine dehydratase Enzyme 1.4E-04 0.534 0.769
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SORD Q00796 sorbitol dehydrogenase Enzyme 4.5E-08 0.552 0.769
TMEM127 O75204 transmembrane protein 127 1.3E-02 0.638 0.615
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962