Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962