Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CEL P19835 carboxyl ester lipase 1.5E-06 0.514 0.808
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GHSR Q92847 growth hormone secretagogue receptor G-protein coupled receptor 6.6E-03 0.528 0.769
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846