Disease: Prolactinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
H3P23 H3 histone pseudogene 23 0.443 0.769
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
IL6 P05231 interleukin 6 0.32 0.248 0.962
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885