Disease: Opiate Addiction
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
ARRB2 P32121 arrestin beta 2 Enzyme modulator 0.51 0.561 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CARTPT Q16568 CART prepropeptide 9.4E-02 0.576 0.692
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846
GRM7 Q14831 glutamate metabotropic receptor 7 G-protein coupled receptor 1.00 0.628 0.538
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NRXN3 Q9HDB5 Q9Y4C0 neurexin 3 1.00 0.656 0.615
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
OR2AG1 Q9H205 olfactory receptor family 2 subfamily AG member 1 (gene/pseudogene) G-protein coupled receptor 3.1E-11 0.582 0.808
PPP1R1B Q9UD71 protein phosphatase 1 regulatory inhibitor subunit 1B Enzyme modulator 0.24 0.617 0.500
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
TPH1 P17752 tryptophan hydroxylase 1 3.2E-07 0.553 0.731