Disease: Overweight and obesity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
ADRB3 P13945 adrenoceptor beta 3 G-protein coupled receptor 2.5E-07 0.533 0.731
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCK P06307 cholecystokinin 3.3E-05 0.453 0.846
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
GCG P01275 glucagon 3.5E-02 0.431 0.885
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
INSRR P14616 insulin receptor related receptor Kinase 5.4E-24 0.508 0.808
IRS2 Q9Y4H2 insulin receptor substrate 2 0.99 0.535 0.654
LEP P41159 leptin 0.46 0.349 0.846
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808
MC4R P32245 melanocortin 4 receptor G-protein coupled receptor 9.2E-04 0.535 0.692
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
SHBG P04278 sex hormone binding globulin 1.3E-06 0.438 0.808
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
UCP2 P55851 uncoupling protein 2 Transporter 1.5E-10 0.493 0.808