Disease: Cocaine Abuse
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCKBR P32239 cholecystokinin B receptor G-protein coupled receptor 2.1E-06 0.573 0.615
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
GABBR1 Q9UBS5 gamma-aminobutyric acid type B receptor subunit 1 G-protein coupled receptor 1.00 0.587 0.769
GABRG2 P18507 gamma-aminobutyric acid type A receptor subunit gamma2 Ion channel 0.74 0.548 0.654
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
NPS P0C0P6 neuropeptide S 1.4E-04 0.619 0.615
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846