Disease: Heroin Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BDNF-AS BDNF antisense RNA 0.638 0.538
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DLG4 P78352 discs large MAGUK scaffold protein 4 Receptor 1.00 0.595 0.654
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
ELK3 P41970 ETS transcription factor ELK3 Transcription factor 8.4E-02 0.490 0.846
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
HTR3B O95264 5-hydroxytryptamine receptor 3B Ion channel 2.5E-07 0.678 0.423
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NTF3 P20783 neurotrophin 3 Signaling 0.93 0.519 0.808
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
OR2AG1 Q9H205 olfactory receptor family 2 subfamily AG member 1 (gene/pseudogene) G-protein coupled receptor 3.1E-11 0.582 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
STIN2-VNTR serotonin transporter intronic VNTR enhancer 0.636 0.538
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654