Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
TNFRSF11B | O00300 | TNF receptor superfamily member 11b | 0.16 | 0.422 | 0.808 | |
RPE65 | Q16518 | retinoid isomerohydrolase RPE65 | Enzyme | 6.5E-14 | 0.417 | 0.808 |
IFNB1 | P01574 | interferon beta 1 | 0.421 | 0.846 | ||
COX1 | P00395 | cytochrome c oxidase subunit I | Enzyme | 0.441 | 0.885 | |
CHD7 | Q9P2D1 | chromodomain helicase DNA binding protein 7 | 1.00 | 0.441 | 0.846 | |
SPG7 | Q9UQ90 | SPG7 matrix AAA peptidase subunit, paraplegin | Enzyme | 2.0E-36 | 0.436 | 0.885 |
TBX1 | O43435 | T-box transcription factor 1 | Transcription factor | 0.84 | 0.433 | 0.808 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
DECR1 | Q16698 | 2,4-dienoyl-CoA reductase 1 | Enzyme | 4.5E-14 | 0.426 | 0.885 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
CYP2B6 | P20813 | cytochrome P450 family 2 subfamily B member 6 | 1.9E-10 | 0.428 | 0.846 | |
GLB1 | P16278 | galactosidase beta 1 | Enzyme | 7.9E-10 | 0.448 | 0.808 |
ARSA | P15289 | arylsulfatase A | Enzyme | 1.1E-11 | 0.448 | 0.923 |
YAP1 | P46937 | Yes associated protein 1 | Enzyme modulator | 1.00 | 0.432 | 0.808 |
WWOX | Q9NZC7 | WW domain containing oxidoreductase | Enzyme | 1.2E-15 | 0.453 | 0.808 |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
SDHD | O14521 | succinate dehydrogenase complex subunit D | Transporter | 0.34 | 0.472 | 0.885 |
ERCC1 | P07992 | ERCC excision repair 1, endonuclease non-catalytic subunit | Enzyme | 1.6E-07 | 0.445 | 0.846 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
PAX6 | P26367 | paired box 6 | 1.00 | 0.450 | 0.769 |