Disease: Alzheimer disease, familial, type 3
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ARR3 P36575 arrestin 3 Enzyme modulator 0.10 0.460 0.846
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885
CXADR P78310 CXADR Ig-like cell adhesion molecule 0.37 0.454 0.885
CXADRP1 CXADR pseudogene 1 0.463 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
IFNG P01579 interferon gamma 0.47 0.288 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
INS P01308 insulin 0.30 0.445 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NR1I3 Q14994 nuclear receptor subfamily 1 group I member 3 Nuclear receptor 3.5E-08 0.448 0.846
NRGN Q92686 neurogranin 0.48 0.608 0.615
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TRIM13 O60858 tripartite motif containing 13 0.64 0.462 0.846