Disease: Intervertebral disc disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846
ADAMTS3 O15072 ADAM metallopeptidase with thrombospondin type 1 motif 3 Enzyme 1.0E-10 0.581 0.808
ADAMTS4 O75173 ADAM metallopeptidase with thrombospondin type 1 motif 4 Enzyme 2.0E-06 0.582 0.692
ADAMTS5 Q9UNA0 ADAM metallopeptidase with thrombospondin type 1 motif 5 Enzyme 8.0E-07 0.597 0.654
ASPN Q9BXN1 asporin 1.0E-07 0.636 0.500
CCL3 P10147 C-C motif chemokine ligand 3 Signaling 0.35 0.460 0.885
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
COL9A2 Q14055 collagen type IX alpha 2 chain 1.0E-08 0.572 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TNFAIP6 P98066 TNF alpha induced protein 6 1.1E-06 0.582 0.731
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962