Disease: Idiopathic osteoarthritis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BID P55957 BH3 interacting domain death agonist 1.6E-11 0.555 0.808
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
COL9A1 P20849 collagen type IX alpha 1 chain 3.1E-19 0.566 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FRZB Q92765 frizzled related protein 1.1E-03 0.573 0.654
GDF5 P43026 growth differentiation factor 5 Signaling 0.67 0.511 0.692
GNL3 Q9BVP2 G protein nucleolar 3 2.0E-19 0.579 0.577
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
PHB P35232 prohibitin 0.76 0.511 0.846
PITX1 P78337 paired like homeodomain 1 0.88 0.561 0.654
SFRP4 Q6FHJ7 secreted frizzled related protein 4 9.3E-05 0.524 0.654
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
TLR10 Q9BXR5 toll like receptor 10 3.5E-09 0.592 0.654
TNFAIP6 P98066 TNF alpha induced protein 6 1.1E-06 0.582 0.731