Disease: Bone Diseases
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
P3H1 Q32P28 prolyl 3-hydroxylase 1 Extracellular structure 2.3E-20 0.736 0.231
SP7 Q8TDD2 Sp7 transcription factor Nucleic acid binding 0.58 0.711 0.462
PLS3 P13797 plastin 3 Cellular structure 0.99 0.656 0.500
WWTR1 Q9GZV5 WW domain containing transcription regulator 1 Enzyme modulator 0.94 0.529 0.615
CRTAP O75718 cartilage associated protein Extracellular structure 5.5E-04 0.636 0.654
ALPL P05186 alkaline phosphatase, biomineralization associated Enzyme 3.6E-04 0.546 0.769
BMP1 P13497 bone morphogenetic protein 1 8.9E-04 0.554 0.769
SERPINH1 P50454 serpin family H member 1 Enzyme modulator 2.8E-02 0.545 0.769
WNT1 P04628 Wnt family member 1 Signaling 0.33 0.495 0.769
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
LRP6 O75581 LDL receptor related protein 6 0.70 0.536 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
SPARC P09486 secreted protein acidic and cysteine rich Signaling 0.89 0.445 0.846
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
PNPLA2 Q96AD5 patatin like phospholipase domain containing 2 Enzyme 4.1E-03 0.511 0.846
MIR29B1 microRNA 29b-1 0.485 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
BEST1 O76090 bestrophin 1 Ion channel 1.8E-12 0.465 0.885
MIR29B2 microRNA 29b-2 0.484 0.885