Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
FOLR1 P15328 folate receptor alpha 0.13 0.522 0.885
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
DHFR P00374 dihydrofolate reductase Enzyme 3.4E-02 0.513 0.808
PRDX2 P32119 peroxiredoxin 2 Enzyme 8.7E-02 0.474 0.885
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
LOX P28300 lysyl oxidase 0.99 0.447 0.846
EIF2S1 P05198 eukaryotic translation initiation factor 2 subunit alpha Nucleic acid binding 0.97 0.587 0.692
CYP3A4 P08684 cytochrome P450 family 3 subfamily A member 4 Enzyme 5.8E-11 0.462 0.885
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808