Disease: HER2 gene amplification
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CISH Q9NSE2 cytokine inducible SH2 containing protein Enzyme modulator 5.4E-04 0.500 0.808
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FGF3 P11487 fibroblast growth factor 3 Signaling 9.3E-05 0.505 0.808
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
H3P23 H3 histone pseudogene 23 0.443 0.769
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
HMGA1 P17096 high mobility group AT-hook 1 Nucleic acid binding 0.83 0.494 0.769
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
INTS2 Q9H0H0 integrator complex subunit 2 1.00 0.590 0.654
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808