Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
C5 P01031 complement C5 Enzyme modulator 8.1E-24 0.550 0.731
CFB P00751 complement factor B 4.7E-16 0.532 0.769
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
IFNG P01579 interferon gamma 0.47 0.288 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
MVK Q03426 mevalonate kinase Kinase 0.17 0.576 0.731
RIPK2 O43353 receptor interacting serine/threonine kinase 2 Kinase 0.39 0.587 0.769
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962