Disease: Neurofibromatosis 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GNRH1 P01148 gonadotropin releasing hormone 1 0.15 0.524 0.731
H3P10 H3 histone pseudogene 10 0.350 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MEN1 O00255 menin 1 1.00 0.444 0.808
MFAP1 P55081 microfibril associated protein 1 Extracellular structure 0.80 0.431 0.846
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PNMT P11086 phenylethanolamine N-methyltransferase Enzyme 5.0E-03 0.653 0.538