Disease: Von Hippel-Lindau Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
GCG P01275 glucagon 3.5E-02 0.431 0.885
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
MEN1 O00255 menin 1 1.00 0.444 0.808
TGM2 P21980 transglutaminase 2 Enzyme 6.8E-18 0.445 0.808
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846