Disease: Myeloproliferative disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
L3MBTL1 Q9Y468 L3MBTL histone methyl-lysine binding protein 1 Epigenetic regulator 1.5E-12 0.729 0.269
IRAK2 O43187 interleukin 1 receptor associated kinase 2 Kinase 2.6E-19 0.722 0.385
HBS1L Q9Y450 HBS1 like translational GTPase Enzyme 1.9E-07 0.705 0.462
BCAM P50895 basal cell adhesion molecule (Lutheran blood group) Cell adhesion 1.1E-08 0.666 0.462
NFE2 Q16621 nuclear factor, erythroid 2 Enzyme 0.67 0.628 0.577
PRB1 P04280 proline rich protein BstNI subfamily 1 (gene/pseudogene) 8.4E-11 0.621 0.692
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
CD177 Q8N6Q3 CD177 molecule 0.595 0.654
FIP1L1 Q6UN15 factor interacting with PAPOLA and CPSF1 0.79 0.575 0.577
MVD P53602 mevalonate diphosphate decarboxylase 2.7E-17 0.568 0.769
ULK1 O75385 unc-51 like autophagy activating kinase 1 Kinase 0.99 0.564 0.769
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
SOCS2 O14508 suppressor of cytokine signaling 2 Enzyme modulator 0.63 0.560 0.731
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
EPOR P19235 erythropoietin receptor Receptor 1.0E-02 0.526 0.692
CHIT1 Q13231 chitinase 1 7.2E-16 0.525 0.692
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
THPO P40225 thrombopoietin 0.20 0.513 0.692
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
HBA1 P69905 hemoglobin subunit alpha 1 6.7E-03 0.508 0.808
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769