Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
CAT | P04040 | catalase | Enzyme | 1.6E-10 | 0.359 | 0.962 |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
FAS | P25445 | Fas cell surface death receptor | 0.81 | 0.372 | 0.923 | |
GJA1 | P17302 | gap junction protein alpha 1 | Cell-cell junction | 0.16 | 0.393 | 0.885 |
FGF2 | P09038 | fibroblast growth factor 2 | Signaling | 1.8E-02 | 0.383 | 0.923 |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
FOS | P01100 | Fos proto-oncogene, AP-1 transcription factor subunit | Transcription factor | 0.26 | 0.411 | 0.885 |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
GJB2 | P29033 | gap junction protein beta 2 | Cell-cell junction | 6.6E-16 | 0.441 | 0.846 |
AFP | P02771 | alpha fetoprotein | Transporter | 1.1E-11 | 0.429 | 0.885 |
GDF15 | Q99988 | growth differentiation factor 15 | Signaling | 3.0E-07 | 0.429 | 0.808 |
NPY | P01303 | neuropeptide Y | Signaling | 0.14 | 0.447 | 0.846 |
KLK3 | P07288 | kallikrein related peptidase 3 | Enzyme | 4.4E-06 | 0.443 | 0.885 |
ANGPT1 | Q15389 | angiopoietin 1 | Signaling | 0.95 | 0.446 | 0.808 |