Disease: Agenesis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZEB1 P37275 zinc finger E-box binding homeobox 1 Transcription factor 0.97 0.442 0.808
WNT10A Q9GZT5 Wnt family member 10A Signaling 4.2E-09 0.547 0.731
WNT1 P04628 Wnt family member 1 Signaling 0.33 0.495 0.769
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFB3 P10600 transforming growth factor beta 3 Signaling 0.99 0.498 0.808
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
SYBU Q9NX95 syntabulin Transporter 9.8E-05 0.546 0.769
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
SIX1 Q15475 SIX homeobox 1 Transcription factor 0.65 0.496 0.692
RUNX3 Q13761 RUNX family transcription factor 3 Transcription factor 0.84 0.459 0.731
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
RMDN3 Q96TC7 regulator of microtubule dynamics 3 5.2E-05 0.534 0.769
RMDN2 Q96LZ7 regulator of microtubule dynamics 2 4.4E-24 0.531 0.769
RMDN1 Q96DB5 regulator of microtubule dynamics 1 5.9E-10 0.546 0.769
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731
MSC O60682 musculin 2.5E-02 0.475 0.846
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MIR221 microRNA 221 0.449 0.846
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
LRP6 O75581 LDL receptor related protein 6 0.70 0.536 0.808