Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
NFKB1 | P19838 | nuclear factor kappa B subunit 1 | Transcription factor | 1.00 | 0.396 | 0.923 |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
COL1A1 | P02452 | collagen type I alpha 1 chain | 1.00 | 0.430 | 0.808 | |
WNK1 | Q9H4A3 | WNK lysine deficient protein kinase 1 | Kinase | 1.00 | 0.416 | 0.846 |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
SETD2 | Q9BYW2 | SET domain containing 2, histone lysine methyltransferase | Epigenetic regulator | 1.00 | 0.424 | 0.846 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
PTPRC | P08575 | protein tyrosine phosphatase receptor type C | Enzyme | 1.00 | 0.435 | 0.808 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
BRD4 | O60885 | bromodomain containing 4 | Epigenetic regulator | 1.00 | 0.446 | 0.885 |
PRKCB | P05771 | protein kinase C beta | Kinase | 1.00 | 0.453 | 0.885 |
COL3A1 | P02461 | collagen type III alpha 1 chain | 1.00 | 0.477 | 0.808 | |
HDAC6 | Q9UBN7 | histone deacetylase 6 | Epigenetic regulator | 1.00 | 0.465 | 0.846 |
COL1A2 | P08123 | collagen type I alpha 2 chain | 1.00 | 0.486 | 0.846 | |
HDAC4 | P56524 | histone deacetylase 4 | Epigenetic regulator | 1.00 | 0.484 | 0.885 |
FASN | P49327 | fatty acid synthase | Enzyme | 1.00 | 0.474 | 0.846 |
RASA1 | P20936 | RAS p21 protein activator 1 | Enzyme modulator | 1.00 | 0.481 | 0.885 |