Disease: Spastic gait
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
ZFYVE26 Q68DK2 zinc finger FYVE-type containing 26 4.7E-23 0.636 0.615
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
WASHC5 Q12768 WASH complex subunit 5 Transporter 8.3E-18 0.572 0.615
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
DDHD2 O94830 DDHD domain containing 2 Enzyme 1.4E-10 0.695 0.577
ZFYVE27 Q5T4F4 zinc finger FYVE-type containing 27 1.1E-09 0.805 0.308
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
CPT1C Q8TCG5 carnitine palmitoyltransferase 1C Enzyme 2.2E-09 0.691 0.500
PGAP1 Q75T13 post-GPI attachment to proteins inositol deacylase 1 Transporter 3.2E-08 0.650 0.423
SPART Q8N0X7 spartin 3.0E-07 0.588 0.654
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
B4GALNT1 Q00973 beta-1,4-N-acetyl-galactosaminyltransferase 1 3.9E-05 0.644 0.615
SLC33A1 O00400 solute carrier family 33 member 1 Transporter 9.9E-05 0.529 0.769
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
CYP2U1 Q7Z449 cytochrome P450 family 2 subfamily U member 1 1.4E-03 0.722 0.462
VAMP1 P23763 vesicle associated membrane protein 1 3.9E-03 0.628 0.538
NIPA1 Q7RTP0 NIPA magnesium transporter 1 Transporter 5.9E-03 0.682 0.462
GJC2 Q5T442 gap junction protein gamma 2 Cell-cell junction 1.0E-02 0.593 0.692
KCNA1 Q09470 potassium voltage-gated channel subfamily A member 1 Ion channel 7.6E-02 0.573 0.577
ERLIN1 O75477 ER lipid raft associated 1 0.18 0.736 0.308
C19orf12 Q9NSK7 chromosome 19 open reading frame 12 0.34 0.641 0.615