Disease: Proliferative vitreoretinopathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CAPN5 O15484 calpain 5 Enzyme 2.5E-08 0.663 0.615
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CXCL1 P09341 C-X-C motif chemokine ligand 1 Signaling 0.12 0.449 0.923
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL6ST P40189 interleukin 6 signal transducer Signaling 1.00 0.475 0.808
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846
LRPPRC P42704 leucine rich pentatricopeptide repeat containing 2.3E-10 0.493 0.769
LTA P01374 lymphotoxin alpha Signaling 0.20 0.434 0.885
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NM neutrophil migration 0.473 0.808
PVR P15151 PVR cell adhesion molecule 3.9E-10 0.510 0.769
RPE Q96AT9 ribulose-5-phosphate-3-epimerase 2.5E-04 0.575 0.538
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885