Disease: Seizures
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GLUL P15104 glutamate-ammonia ligase Enzyme 1.00 0.513 0.731
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
GRIK1 P39086 glutamate ionotropic receptor kainate type subunit 1 Ion channel 1.2E-09 0.641 0.462
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
KAT8 Q9H7Z6 lysine acetyltransferase 8 0.22 0.592 0.654
KCNQ2 O43526 potassium voltage-gated channel subfamily Q member 2 Ion channel 1.00 0.537 0.654
LEP P41159 leptin 0.46 0.349 0.846
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
NTNG2 Q96CW9 netrin G2 Enzyme modulator 1.00 0.700 0.423
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PVALB P20472 parvalbumin Calcium-binding protein 8.7E-02 0.547 0.692
REST Q13127 RE1 silencing transcription factor Transcription factor 0.99 0.535 0.808
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
SLC12A5 Q9H2X9 solute carrier family 12 member 5 Transporter 1.00 0.570 0.654