Disease: Absence Seizures
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SIK1 A0A0B4J2F2 P57059 salt inducible kinase 1 Kinase 0.94 0.544 0.731
CHD2 O14647 chromodomain helicase DNA binding protein 2 1.00 0.585 0.577
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808
KCNQ2 O43526 potassium voltage-gated channel subfamily Q member 2 Ion channel 1.00 0.537 0.654
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
GNAO1 P09471 G protein subunit alpha o1 Enzyme modulator 0.99 0.523 0.808
GABRA1 P14867 gamma-aminobutyric acid type A receptor subunit alpha1 Ion channel 0.91 0.563 0.577
LAMA2 P24043 laminin subunit alpha 2 Enzyme modulator 2.4E-47 0.553 0.692
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
CLCN4 P51793 chloride voltage-gated channel 4 Ion channel 1.00 0.587 0.654
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
PIGP P57054 phosphatidylinositol glycan anchor biosynthesis class P 1.9E-03 0.633 0.462
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538
KCNA1 Q09470 potassium voltage-gated channel subfamily A member 1 Ion channel 7.6E-02 0.573 0.577
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615
NEUROD2 Q15784 neuronal differentiation 2 Enzyme 0.94 0.619 0.538
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808