Disease: Tonic - clonic seizures
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
GNAO1 P09471 G protein subunit alpha o1 Enzyme modulator 0.99 0.523 0.808
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615
TBC1D24 Q9ULP9 TBC1 domain family member 24 Enzyme modulator 1.3E-08 0.530 0.808
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
TRNL1 tRNA 0.534 0.731
KCNQ2 O43526 potassium voltage-gated channel subfamily Q member 2 Ion channel 1.00 0.537 0.654
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615