Disease: Developmental regression
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
SCN1A P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 1.00 0.477 0.808
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
GNAO1 P09471 G protein subunit alpha o1 Enzyme modulator 0.99 0.523 0.808
TBC1D24 Q9ULP9 TBC1 domain family member 24 Enzyme modulator 1.3E-08 0.530 0.808
ND5 P03915 NADH dehydrogenase, subunit 5 (complex I) Enzyme 0.531 0.769
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
TRNL1 tRNA 0.534 0.731
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808
SIK1 A0A0B4J2F2 P57059 salt inducible kinase 1 Kinase 0.94 0.544 0.731
ND4 P03905 NADH dehydrogenase, subunit 4 (complex I) Enzyme 0.546 0.769
PNKP Q96T60 polynucleotide kinase 3'-phosphatase 3.7E-14 0.553 0.692
TRNW tRNA 0.563 0.731
NDP Q00604 norrin cystine knot growth factor NDP 0.65 0.566 0.692