Disease: Colorectal Neoplasms
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
POLE Q07864 DNA polymerase epsilon, catalytic subunit 8.0E-27 0.526 0.731
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
SELENBP1 Q13228 selenium binding protein 1 Immune response 3.2E-16 0.493 0.846
XAF1 Q6GPH4 XIAP associated factor 1 6.8E-12 0.587 0.769
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
WIF1 Q9Y5W5 WNT inhibitory factor 1 Calcium-binding protein 1.3E-09 0.507 0.731
CYP2A6 P11509 cytochrome P450 family 2 subfamily A member 6 5.4E-09 0.556 0.731
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
DPAGT1 Q9H3H5 dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 Enzyme 1.1E-05 0.621 0.538
UMPS P11172 uridine monophosphate synthetase 1.1E-04 0.584 0.615
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
PYCARD Q9ULZ3 PYD and CARD domain containing Enzyme 2.0E-04 0.457 0.808
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731
CDH1 P12830 cadherin 1 0.15 0.401 0.808
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769
LRRC3B Q96PB8 leucine rich repeat containing 3B Receptor 0.44 0.695 0.308
GREM1 O60565 gremlin 1, DAN family BMP antagonist 0.47 0.508 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962