Disease: Motor symptoms
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFL P07196 neurofilament light 0.488 0.769
PAFAH1B1 P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 1.00 0.504 0.769
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PYCARD Q9ULZ3 PYD and CARD domain containing Enzyme 2.0E-04 0.457 0.808
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TGM2 P21980 transglutaminase 2 Enzyme 6.8E-18 0.445 0.808
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885