Disease: Behavioral variant of frontotemporal dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MOBP Q13875 myelin associated oligodendrocyte basic protein Cellular structure 0.55 0.700 0.423
NEFL P07196 neurofilament light 0.488 0.769
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
TMEM106B Q9NUM4 transmembrane protein 106B 0.33 0.590 0.462
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769