Disease: Vasculitis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WG Wegener granulomatosis 0.595 0.808
ABCC11 Q96J66 ATP binding cassette subfamily C member 11 Transporter 4.0E-46 0.565 0.769
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
F5 P12259 coagulation factor V Enzyme 5.9E-15 0.441 0.846
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
ADA P00813 adenosine deaminase Enzyme 2.9E-12 0.440 0.885
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ADA2 Q9NZK5 adenosine deaminase 2 Enzyme 8.1E-08 0.545 0.846
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769
HLA-DPA1 P20036 major histocompatibility complex, class II, DP alpha 1 Immune response 2.5E-06 0.552 0.846
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
PTX3 P26022 pentraxin 3 7.0E-05 0.457 0.808
IL12B P29460 interleukin 12B Signaling 1.1E-04 0.480 0.885
GCA P28676 grancalcin 1.4E-04 0.590 0.731
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923