Disease: Spastic Paraplegia, Hereditary
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AAAS Q9NRG9 aladin WD repeat nucleoporin 2.4E-13 0.601 0.654
ALDH18A1 P54886 aldehyde dehydrogenase 18 family member A1 Enzyme 8.1E-04 0.551 0.769
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
ATL1 Q8WXF7 atlastin GTPase 1 Enzyme modulator 0.98 0.593 0.654
ATP1A1 P05023 ATPase Na+/K+ transporting subunit alpha 1 Transporter 1.00 0.601 0.808
B4GALNT1 Q00973 beta-1,4-N-acetyl-galactosaminyltransferase 1 3.9E-05 0.644 0.615
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
C19orf12 Q9NSK7 chromosome 19 open reading frame 12 0.34 0.641 0.615
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
CYP7B1 O75881 cytochrome P450 family 7 subfamily B member 1 Enzyme 3.3E-06 0.563 0.692
DDHD1 Q8NEL9 DDHD domain containing 1 Enzyme 0.90 0.716 0.423
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
DYNC1H1 Q14204 dynein cytoplasmic 1 heavy chain 1 Enzyme 1.00 0.547 0.769
ERLIN2 O94905 ER lipid raft associated 2 6.7E-04 0.647 0.500
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
GBA2 Q9HCG7 glucosylceramidase beta 2 2.0E-20 0.636 0.654
GJC2 Q5T442 gap junction protein gamma 2 Cell-cell junction 1.0E-02 0.593 0.692
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808
IBA57 Q5T440 iron-sulfur cluster assembly factor IBA57 8.4E-03 0.666 0.423
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
NEFL P07196 neurofilament light 0.488 0.769
NIPA1 Q7RTP0 NIPA magnesium transporter 1 Transporter 5.9E-03 0.682 0.462
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769