Disease: Inherited neuropathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APTX Q7Z2E3 aprataxin Nucleic acid binding 4.0E-10 0.590 0.500
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
BSCL2 Q96G97 BSCL2 lipid droplet biogenesis associated, seipin 1.1E-09 0.545 0.692
COQ8A Q8NI60 coenzyme Q8A Kinase 9.3E-11 0.674 0.385
EGR2 P11161 early growth response 2 Nucleic acid binding 0.50 0.547 0.769
FBLN5 Q9UBX5 fibulin 5 Calcium-binding protein 1.00 0.546 0.692
FGF14 Q92915 fibroblast growth factor 14 Signaling 0.91 0.619 0.692
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
GAN Q9H2C0 gigaxonin 2.5E-02 0.674 0.500
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
INF2 Q27J81 inverted formin, FH2 and WH2 domain containing 0.97 0.644 0.423
KARS1 Q15046 lysyl-tRNA synthetase 1 Enzyme 4.2E-09 0.636 0.577
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
LITAF Q99732 lipopolysaccharide induced TNF factor Transcription factor 3.1E-02 0.650 0.462
LMNA P02545 lamin A/C 1.00 0.384 0.885
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
MPZ P25189 myelin protein zero 0.27 0.503 0.846
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808