Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
SDHC Q99643 succinate dehydrogenase complex subunit C 2.0E-04 0.517 0.846
CEP290 O15078 centrosomal protein 290 1.1E-60 0.517 0.769
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
ABCC9 O60706 ATP binding cassette subfamily C member 9 Transporter 9.4E-09 0.552 0.692
RPGRIP1L Q68CZ1 RPGRIP1 like Enzyme modulator 4.1E-31 0.534 0.769
CSPP1 Q1MSJ5 centrosome and spindle pole associated protein 1 3.3E-29 0.544 0.769
CC2D2A Q9P2K1 coiled-coil and C2 domain containing 2A 1.7E-27 0.532 0.692
TMEM216 Q9P0N5 transmembrane protein 216 1.9E-03 0.544 0.615
RAB3GAP2 Q9H2M9 RAB3 GTPase activating non-catalytic protein subunit 2 Enzyme modulator 0.99 0.584 0.769
RAB3GAP1 Q15042 RAB3 GTPase activating protein catalytic subunit 1 1.5E-07 0.566 0.692
CEP55 Q53EZ4 centrosomal protein 55 2.0E-12 0.534 0.731
TMEM231 Q9H6L2 transmembrane protein 231 3.1E-07 0.554 0.692
RPGRIP1 Q96KN7 RPGR interacting protein 1 Enzyme modulator 1.3E-23 0.553 0.654
KDM5C P41229 lysine demethylase 5C 1.00 0.581 0.538
TCTN2 Q96GX1 tectonic family member 2 1.8E-14 0.578 0.654