Disease: Pruritus
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AQP5 P55064 aquaporin 5 Ion channel 5.3E-02 0.552 0.769
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CDSN Q15517 corneodesmosin 0.46 0.585 0.731
CLEC7A Q9BXN2 C-type lectin domain containing 7A 5.5E-12 0.553 0.769
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
DSG4 Q86SJ6 desmoglein 4 Cell adhesion 5.9E-13 0.686 0.423
F2RL1 P55085 F2R like trypsin receptor 1 G-protein coupled receptor 1.5E-04 0.480 0.769
FECH P22830 ferrochelatase Enzyme 2.8E-03 0.585 0.577
IL17F Q96PD4 interleukin 17F 3.9E-02 0.480 0.808
IL17RA Q96F46 interleukin 17 receptor A 3.6E-04 0.529 0.808
IL17RC Q8NAC3 interleukin 17 receptor C 2.3E-14 0.633 0.615
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
LIPN Q5VXI9 lipase family member N 3.1E-05 0.736 0.423
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MVK Q03426 mevalonate kinase Kinase 0.17 0.576 0.731
NLRC4 Q9NPP4 NLR family CARD domain containing 4 9.9E-12 0.556 0.769
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
PEPD P12955 peptidase D Enzyme 1.5E-14 0.621 0.769
PKP1 Q13835 plakophilin 1 Cellular structure 5.8E-04 0.659 0.462
SCN10A Q9Y5Y9 sodium voltage-gated channel alpha subunit 10 Ion channel 9.9E-38 0.566 0.692
SCN11A Q9UI33 sodium voltage-gated channel alpha subunit 11 Ion channel 6.9E-26 0.666 0.462
SCN9A Q15858 sodium voltage-gated channel alpha subunit 9 Ion channel 4.8E-19 0.543 0.615
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923