Disease: Bicuspid aortic valve
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CHST3 Q7LGC8 carbohydrate sulfotransferase 3 7.2E-03 0.517 0.846
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
ELN P15502 elastin 2.1E-14 0.415 0.885
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
FOSB P53539 FosB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.98 0.463 0.846
GJA8 P48165 gap junction protein alpha 8 Cell-cell junction 2.2E-03 0.587 0.577
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885
JUNB P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.86 0.467 0.769
JUND P17535 JunD proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.70 0.475 0.808
MFAP5 Q13361 microfibril associated protein 5 5.1E-03 0.590 0.615
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923
TNC P24821 tenascin C 1.3E-07 0.433 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923