Disease: Familial Alzheimer Disease (FAD)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ADI1 Q9BV57 acireductone dioxygenase 1 Enzyme 3.2E-05 0.674 0.654
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
DOCK3 Q8IZD9 dedicator of cytokinesis 3 1.00 0.619 0.692
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PRKCA P17252 protein kinase C alpha Kinase 0.37 0.440 0.846
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PYCARD Q9ULZ3 PYD and CARD domain containing Enzyme 2.0E-04 0.457 0.808
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885