Disease: Pregnancy associated hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
FLT1 P17948 fms related receptor tyrosine kinase 1 Kinase 1.00 0.419 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
TIMP1 P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 0.50 0.380 0.885
TIMP2 P16035 TIMP metallopeptidase inhibitor 2 Enzyme modulator 0.79 0.425 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VEGFC P49767 vascular endothelial growth factor C Signaling 0.50 0.459 0.769