Disease: Coloboma of iris
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
DLL1 O00548 delta like canonical Notch ligand 1 1.00 0.492 0.808
SEMA3E O15041 semaphorin 3E Signaling 8.7E-09 0.515 0.769
FKTN O75072 fukutin 8.7E-07 0.511 0.692
FOXH1 O75593 forkhead box H1 4.2E-02 0.615 0.654
SIX3 O95343 SIX homeobox 3 Transcription factor 0.95 0.560 0.692
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769
LARGE1 O95461 LARGE xylosyl- and glucuronyltransferase 1 Enzyme 0.99 0.526 0.654
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
TDGF1 P13385 teratocarcinoma-derived growth factor 1 Calcium-binding protein 9.2E-11 0.584 0.731
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
GAS1 P54826 growth arrest specific 1 0.82 0.587 0.654
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846
TGIF1 Q15583 TGFB induced factor homeobox 1 Enzyme 1.0E-02 0.588 0.769
TCTN1 Q2MV58 tectonic family member 1 1.1E-15 0.597 0.615
CDON Q4KMG0 cell adhesion associated, oncogene regulated 2.1E-15 0.601 0.731
B3GALNT2 Q8NCR0 beta-1,3-N-acetylgalactosaminyltransferase 2 Enzyme 2.8E-07 0.578 0.577
POMGNT1 Q8WZA1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 1.9E-20 0.537 0.538
DISP1 Q96F81 dispatched RND transporter family member 1 8.9E-08 0.644 0.692
NODAL Q96S42 nodal growth differentiation factor Signaling 0.97 0.588 0.731