Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
SIRT1 | Q96EB6 | sirtuin 1 | Epigenetic regulator | 8.7E-02 | 0.378 | 0.885 |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
PRKAR1A | P10644 | protein kinase cAMP-dependent type I regulatory subunit alpha | 1.00 | 0.401 | 0.846 | |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
CASR | P41180 | calcium sensing receptor | G-protein coupled receptor | 4.7E-02 | 0.410 | 0.846 |
HSP90AA1 | P07900 | heat shock protein 90 alpha family class A member 1 | Chaperone | 0.86 | 0.411 | 0.923 |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
SPG7 | Q9UQ90 | SPG7 matrix AAA peptidase subunit, paraplegin | Enzyme | 2.0E-36 | 0.436 | 0.885 |
HMGA2 | P52926 | high mobility group AT-hook 2 | Nucleic acid binding | 0.87 | 0.429 | 0.808 |
MIR145 | microRNA 145 | 0.431 | 0.846 | |||
CSF1R | P07333 | colony stimulating factor 1 receptor | Kinase | 0.13 | 0.448 | 0.808 |
SPARC | P09486 | secreted protein acidic and cysteine rich | Signaling | 0.89 | 0.445 | 0.846 |
PAX6 | P26367 | paired box 6 | 1.00 | 0.450 | 0.769 | |
MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 |
APOB | P04114 | apolipoprotein B | 1.9E-16 | 0.453 | 0.808 | |
PRKAA1 | Q13131 | protein kinase AMP-activated catalytic subunit alpha 1 | Kinase | 0.14 | 0.453 | 0.846 |
FOXM1 | Q08050 | forkhead box M1 | 7.4E-04 | 0.441 | 0.769 | |
NR1I3 | Q14994 | nuclear receptor subfamily 1 group I member 3 | Nuclear receptor | 3.5E-08 | 0.448 | 0.846 |