Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
COPD | Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 | |||
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
IL33 | O95760 | interleukin 33 | 8.3E-10 | 0.409 | 0.885 | |
NGF | P01138 | nerve growth factor | Signaling | 0.82 | 0.391 | 0.885 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
HLA-DRB1 | P01911 | major histocompatibility complex, class II, DR beta 1 | Immune response | 1.1E-03 | 0.333 | 0.923 |
MMP1 | P03956 | matrix metallopeptidase 1 | Enzyme | 7.7E-18 | 0.385 | 0.885 |
IL4 | P05112 | interleukin 4 | 4.7E-03 | 0.332 | 0.962 | |
IL5 | P05113 | interleukin 5 | 5.7E-03 | 0.437 | 0.846 | |
ICAM1 | P05362 | intercellular adhesion molecule 1 | 3.5E-02 | 0.364 | 0.962 | |
ADRB2 | P07550 | adrenoceptor beta 2 | G-protein coupled receptor | 0.53 | 0.442 | 0.923 |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
SCGB1A1 | P11684 | secretoglobin family 1A member 1 | Signaling | 8.0E-04 | 0.546 | 0.808 |
RNASE3 | P12724 | ribonuclease A family member 3 | 0.490 | 0.808 | ||
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 |
CFTR | P13569 | CF transmembrane conductance regulator | Ion channel | 2.2E-58 | 0.424 | 0.885 |
IL9 | P15248 | interleukin 9 | 8.1E-07 | 0.461 | 0.846 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
IL4R | P24394 | interleukin 4 receptor | Receptor | 2.3E-04 | 0.474 | 0.846 |
PDE4A | P27815 | phosphodiesterase 4A | 0.98 | 0.523 | 0.846 | |
IL13 | P35225 | interleukin 13 | 1.4E-02 | 0.386 | 0.846 | |
SFTPD | P35247 | surfactant protein D | Surfactant | 7.5E-05 | 0.500 | 0.846 |
CHI3L1 | P36222 | chitinase 3 like 1 | 1.1E-05 | 0.419 | 0.885 |