Disease: Drug abuse
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808